The devices are designed for detection and quantitative determination of specific DNA (RNA) in the tested samples in a wide dynamic range up to 109 copies.
The devices come in two versions: ANK-16 and ANK-32 for analysis of 16 and 32 samples, respec-tively. They are suitable both for research and routine analyses.
The ANK device consists of a thermal unit, optical unit, and software.
The thermal unit provides an exponential increase of the PCR product (amplicon) amount in the pres-ence of the target DNA (RNA) in the sample.
The optical unit measures the sample fluorescence signal proportional to the amplicon amount in the reaction mixture. Five independent reactions in a given sample can be simultaneously observed due to five–color measurement of the fluorescence signal.
The device software supports setting and control of PCR and fluorescence measurement conditions as well as PCR data processing and output in a specified form.
Medicine, sanitary and epidemiologic control, agriculture, criminalistics, biotechnology, basic research in the field of nucleic acid analysis.
DNA/RNA quantitation from a single to10 –9 copies
up to five-colours fluorescence detection, possibility of detecting a great number of fluorescent dyes – SYBR Green I, FAM, R6G, HEX, JOE, ROX, TAMRA, Cy5, Cy5.5 and other
possibility of multiplex PCR design
high sensitivity of all detection channels, which allows working with down to 0,5 pico-mole probes per reaction
user-friendly, convenient software, modern algorithms of threshold cycles calculation and ability to choose variants of data analysis
reduction of contamination risks, time saving, simplification of PCR-laboratory organization
Registration of Health and Social Development Ministry No. ÔÑ 022 à 2005/2163-05 of August 23, 2005 .
Protected by RF Patent issued 10 Aug, 2007
Institute for Analytical Instrumentation RAS – optical unit and overall adjustment.
Bauman Moscow State Technical University – high-precision programmable thermal unit.
SYNTOL Close Joint–Stock Company – chemical reagents for RT–PCR.
The devices come complete with software, methods package, calibration kit, primers, dyes and other re-agents (from SYNTOL).
Cyclotemp-901 centrifuge for protein and DNA samples preparation (developed by N.E. Bauman Moscow State Technical University ).