Universal instrument for analyzing compound biological solutions: peptides and proteins; nucleic acids ; complex biopolymers; low-molecular biologically active substances; synthetic medicines, etc. NANOFOR 04 is the instrument that realizes capabilities of two techniques : highly efficient liquid chromatography and capillary electrophoresis. Those techniques are easy in application and efficient; they ensure high reproducibility and accuracy of analysis at extremely small sample sizes (about 2 nl) and low cost of consumables. Flexible configurations of the NANOFOR 04 electrochromatograph allows one to use either monolithic capillary columns or conventional capillaries, and also to chose the detector type: spectrophotometric or fluorometric.
Combination of capabilities of two separation techniques : highly efficient liquid chromatography and capillary electrophoresis. Availability of two detectors (spectrophotometric and fluorometric) mounted in the same casing. Ten-fold increase in the analysis sensitivity due to Z-shaped tray. Fast programmable change of the high-voltage power supply polarity (1 second) in order to concentrate the sample within the capillary. Remote access to the analysis results through the Internet or local network
LIF detector
CF detector
High voltage power supply
General characteristics
* Operating wavelengths depend on the types of easily replaceable light filters and vary within the 200 to 600 nm range.
Medical diagnostics, ecology, chemistry, biological technologies, criminalistics and urgent forensic medical examination, food analysis, pharmacology.
ANALYSIS OF THE BLOOD SERUM
BY CAPILLARY ELECTROPHORESIS
1 – g -
globulin (15.35 %); 2 - b - globulin (8.15 %);
3 - a 2- globulin (9.3 %);
RF Patent No. 2182329 "Fluorometric detector"
dated May 10, 2002 . RF Patent No. 2189038 "Spectrometric detector for capillary electrophoresis and capillary liquid chromatography" dated September 10, 2002 .
Institute for Analytical Instrumentation RAS.
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