SOFTWARE  PACKAGE  FOR  DETERMINATION
OF  METABOLITE  CONCENTRATIONS  IN  BRAIN
TISSUE  OF  SEVERAL  VOLUNTEERS  USING
MAGNETIC  RESONANCE  SPECTROSCOPY

Yu. I. Neronov, L. A. Tyutin*, Z. Garaibekh*

 St. Petersburg State University of Information Technologies, Mechanics and Optics
*Central X-Ray Radiology Research Institute, Saint-Petersburg


 


   A "Magnetom Vision" tomograph was used to obtain in vivo magnetic resonance spectra of white brain matter from a group of 16 healthy volunteers 19 to 60 years old. The paper presents a software package for processing these spectra with minimal systematic errors and estimation of confidence levels. For the group tested the mean molar metabolite concentrations (mmol / L) of white brain matter were 10.70 + 1.25 (N-acetyl-aspartate C(NAA)); 6.53 + 0.67 (phosphocreatine C(PCr)); 1.67 + 0.35 (choline C(Cho)); 6.39 + 1.54 (myo-
inositol C(Ins)).