Features of the low mass isotopic mass spectrometry discussed. It`s main applications and problems are con-sidered. Some ways to overcome is stating, particularly nondiscriminational ion source application. Compara-tive analysis of commercial isotopic mass spectrometers carried out. The approach to low mass isotopic mass spectrometers construction on the base of permanent magnet suggested. Keywords: isotopic ratio, light elements, mass discrimination, static mass analyzer

1 - Institute for Analytical Instrumentation RAS, Saint-Petersburg 2 - A.A. Bochvar Russian Institute for Inorganic Materials, Moscow 3 - A.F. Ioffe Phys.-Tech. Institute RAS, Saint-Petersburg

A mathematical model for the energy dispersive x-ray and low energy gamma detector is proposed, which is based on the analysis of the radiation and high energy electron transport in a detector. This model allows to es-timate detector response function parameters. Using Monte Carlo method, probabilities of the photon registra-tion in different parts of the detector response function were determined. The results obtained by this model are compared with experimental data within the energy range up to 2 MeV. Estimation of the limited spatial resolu-tion due the processes of photon scattering and paths of electron deceleration was made. Keywords: detector response function, spatial resolution of detector, detecting of x-ray and gamma rays

Irkutsk State University of Transport

The work describes methods for determination of the phase compensator three complex parameters ρ, ρ1 and ρ2. One of these is based only on positioning procedures and suggests rather expressed imperfection of the com-pensator, which is due to the appreciable difference of the small parameters ρ1 and ρ2 from null. Another method is a combined approach when both positioning procedures and invariants of ellipsometry of isotropic media are used. The process of optical calibration of the non-uniform compensator using both methods is described in de-tails. Keywords: ellipsometry, phase compensator, matrix Jones, optical calibration, optical alignment, ellipsometry invariants

1-Institute of Applied Physics NAS, Ukraine, Sumy 2-Institute for Analytical Instrumentation RAS, Saint-Petersburg

We discuss the use of atomic force microscopy (AFM) in biology, medicine, etc. The point measurement technique for relief, interaction forces and local properties study is suggested. The influence of shear forces is totally eliminated because lateral movement of the probe occurs without contact with the surface. The principle of operation, possibilities and advantages of the method are described. The experimental data confirm the possi-bility of complex approach to AFM study. Keywords: atomic-force microscopy, AFM, force curve, adhesion, elastic properties, topography

Joint-Stock Company \"Nanotechnology-MDT\", Moscow

The algorithm of improving the space resolution in SPM equipped by typical linear optical encoders is sug-gested. The results of this algorithm implementation are demonstrated by the SPM- images of the test objects. Keywords: scanning probe microscopy, optical linear encoders, microscanner, space resolution

1-Institute for Analytical Instrumentation RAS, Saint-Petersburg 2-Saint-Petersburg State University of Information Technologies, Mechanics and Optics 3 -Joint-Stock Company \"Nanotechnology-MDT\", Moscow

Contact angles of water and glycerol droplets are measured for fused silica glass KU-1 before and after the deposition of coatings from chloroform solutions of polystyrene-poly(styrenesulfonic acid) mixtures. The polar component of the surface energy is found to significantly vary for the studied samples linearly decreasing with the growth of the contact angle with water droplets. Silica surface processing with oligomeric diisocyanate CX-100 results in almost complete disappearance of the difference between the measured contact angles for var-ious samples as well as between their γ₂^ν values. γ₂^ν value reaches its maximum with the increase of poly(styrenesulfonic acid) concentration thus allowing the optimization of the polymer mixture composition for fused silica modification at the production of electrochromatographic capillary columns. Keywords: polymer coated, silica glass, capillary columns, electrochromatography

1-Saint-Petersburg State University of Cinema and Television 2-Institute for Analytical Instrumentation RAS, Saint-Petersburg 3-Engineering Technology Center \"RADIANT\", Saint-Petersburg

Design of a collision dissociation cell, operating at high buffer gas pressure, is proposed for a tandem time-of-flight spectrometer with a parallel analysis of parent ions. This device was shown to provide the necessary speed of fragmentation and cleaning of the cell, as well as time confinement of the daughter ion packets. Char-acteristics of ion packets at the exit from the cell are studied. Keywords: collision dissociation cell, collisional cooling, ion packets, tandem TOF mass-spectrometer

Institute for Analytical Instrumentation RAS, Saint-Petersburg

Configuration of a collision dissociation cell with a traveling wave of electric field is proposed for a tandem time-of-flight spectrometer with the parallel analysis of parent ions. The traveling wave is determined by a step-by-step shift of a potential at the electrodes inserted between the quadrupole electrodes of the cell. Traveling wave mode was shown to provide the necessary frequency of daughter ion packets as well as their time con-finement. The characteristics of the ion packets at the exit from the cell are investigated. Keywords: collision dissociation cell, traveling wave of electric field, ion packets, tandem TOF mass-spectrometer

Institute for Analytical Instrumentation RAS, Saint-Petersburg

New method of velocity modulation of the ion beam in a gas-filled transporting interface of a time-of-flight mass spectrometer, aimed at increase of its duty cycle, is proposed, theoretically investigated and experimen-tally tested. Keywords: collision dissociation cell, traveling wave of electric field, ion packets, tandem TOF mass-spectrometer

Institute for Analytical Instrumentation RAS, Saint-Petersburg

The work deals with the problem of fluid flat eigentone production possibility in the restricted cylindrical capillary filled with a fluid. In case when cylinder walls are not absolutely rigid, production of standing flat lon-gitudinal waves is impossible. With cylinder wall density increase approach to a piston standing wave produces an eigentone corresponding to the first natural frequency of a zero radial mode. Examples of calculations of cer-tain capillaries are given. The results of the work may be used in cases of ultrasound application to the problems of particle coagulation. Keywords: resonance, eigentone frequency, eigenfunctions, eigenvalues, flat motion, flat standing waves

Institute for Analytical Instrumentation RAS, Saint-Petersburg

The problem of signal mixture decomposition (with reconstruction of its component forms) is analyzed without any information concerning the proportions and type of mixing. The method is based on using informa-tion criteria and adaptive algorithm for learning neural network. Several forms of distributions were considered for original signals reaching the sensors of information-measurement system. Variations of neural transfer func-tions corresponding to several types of distributions are given. The approach to signal mixture separation in-cludes application of m-gradient in the analysis scheme for independent component analysis. Keywords: signals mixture, separation methods, adaptive algorithms, neural network, m-gradient, independent component analysis

Saint-Petersburg

The problem of detection of local objects, small in comparison with the image size is considered. It is shown that two-stage solution of the problem is necessary — preliminary processing of the image and the search for objects. Preliminary processing includes peaking filtration of the image by Tikhonov or Wiener filter, intended for discerning of conglutinated objects and for their normalization. Besides at this stage the background compo-nent of the image is eliminated. A search algorithm using formation of a threshold surface of detection is de-scribed. It is experimentally shown, that the detection efficiency exceeds 90 %, and the processing time is less than 60 ms for the image size 256 × 256. Keywords: : live cell imaging, analysis of digital image, search of objects, Fourier transform, peaking filtering, threshold surface

Institute for Analytical Instrumentation RAS, Saint-Petersburg

The results of investigation of algorithm on the base of convolution processing signals with derivations of peak signals form for estimation parameters mass-spectra peak in multiplets are discussed. The investigation is realized with the help of computational experiment on the base models of mass-spectral peaks with different amplitudes and different distance between single peaks in multiplets. Keywords: methods for signal processing, mass-spectrometry, peak parameter estimation in multiplets, analysis of algorithm processing data errors

Institute for Analytical Instrumentation RAS, Saint-Petersburg

The results of investigation of algorithms for separate mass spectra data with singlet peaks and mass spectra data with multiplets are discussed. The necessity of these algorithms is due to the fact that time of data proc-essing of multiplet peaks is much longer than that of single peaks, and it’s reasonable to present on-line infor-mation on single peak parameters and then separate peaks off-line and give the final result. Keywords: methods for data processing, mass-spectrometry, evaluation of peak parameters in multiplets

Institute for Analytical Instrumentation RAS, Saint-Petersburg